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Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B.
Wildum, Steffen; Korolowicz, Kyle E; Suresh, Manasa; Steiner, Guido; Dai, Lue; Li, Bin; Yon, Changsuek; De Vera Mudry, Maria Cristina; Regenass-Lechner, Franziska; Huang, Xu; Hong, Xupeng; Murreddu, Marta G; Kallakury, Bhaskar V; Young, John A T; Menne, Stephan.
Affiliation
  • Wildum S; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Korolowicz KE; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Suresh M; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Steiner G; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Dai L; Roche Pharma, Research and Early Development, Roche Innovation Center Shanghai, Shanghai, China.
  • Li B; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Yon C; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • De Vera Mudry MC; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Regenass-Lechner F; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Huang X; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Hong X; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Murreddu MG; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
  • Kallakury BV; Department of Pathology, Georgetown University Medical Center, Washington, DC, United States.
  • Young JAT; Roche Pharma, Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Menne S; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
Front Immunol ; 13: 884113, 2022.
Article in En | MEDLINE | ID: mdl-35677037
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Hepatitis B, Chronic / Toll-Like Receptor 7 / Seroconversion / Marmota Limits: Animals Language: En Journal: Front Immunol Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Hepatitis B, Chronic / Toll-Like Receptor 7 / Seroconversion / Marmota Limits: Animals Language: En Journal: Front Immunol Year: 2022 Document type: Article Affiliation country: Country of publication: